Clinical TrialsGenomic SurveillanceEpidemiological SignalsRegulatory FilingsDrug PipelinesVariant TrackingHealthcare InfrastructureBioeconomic ModelingPhase ProgressionOutbreak PatternsSupply ChainMarket IntelligenceSIR ModelingCompartmental DynamicsClinical TrialsGenomic SurveillanceEpidemiological SignalsRegulatory FilingsDrug PipelinesVariant TrackingHealthcare InfrastructureBioeconomic ModelingPhase ProgressionOutbreak PatternsSupply ChainMarket IntelligenceSIR ModelingCompartmental Dynamics

BIOINT

[SYSTEM] bioint v2.0 · loaded[PIPELINE] ingest → normalize → model → deliver[INGEST] 2.4k sources · 180 signals · active

From disease patterns to drug pipelines to healthcare infrastructure — BioInt turns life-sciences data into decision-grade intelligence. Built for researchers, strategists, and investors who need to see what's coming before it arrives.

BioInt ingests clinical trials, genomic databases, regulatory filings, and market data. It models disease dynamics, R&D success probabilities, and economic impacts — giving you a clear view of the biological and economic forces that shape health outcomes and market outcomes alike.

Methodology

Compartmental modelsSIR, SEIR, agent-based
ForecastingBayesian, ensemble, neural
Entity resolutionFuzzy matching, graph-based
ValidationBacktesting, cross-validation

Epidemic Curve Modeling

Incidence vs. model forecast — surveillance signal integration and early-warning capability. Compartmental dynamics (SIR/SEIR) with Bayesian parameter estimation.

[RESEARCH]

Built for top-tier epidemiologists, computational biologists, and bioengineers. Stochastic ODE solvers, MCMC posterior sampling, particle filtering for state estimation. Integrates with WHO, CDC, ECDC surveillance feeds. Agent-based and metapopulation extensions. Real-time Rt and growth rate estimation.

[SIR/SEIR][MCMC][ODE][Rt][ENSEMBLE]
bioint — epidemic_monitor · devSTREAMING
$ bioint init --env prod
[INIT] loading modules · SIR, SEIR, MCMC, particle_filter
[CONNECT] who::flunet, cdc::nndss, ecdc::tessy — 2.4k sources
$ bioint run --model epidemic --sources who,cdc,ecdc --mcmc 10k
[SIR] Rt=1.12 · forecast active
[ODE] stochastic solver · dt=0.01 · ensemble=100
[DEBUG] Rt CI: [1.08, 1.16] · growth_rate: 0.04
$ bioint stream --table incidence
# streaming incidence · who+cdc+ecdc · last sync: 2m ago
weekincidenceforecaststatus
W11214[OK]
W42826[SYNC]
W84548[OK]
W127271[CACHE]
W169895[OK]
W208588[LIVE]
_awaiting next tick
$
[CLI]
bioint init --env prodLoad SIR/SEIR/MCMC modules
bioint run --model epidemic --mcmc 10kRun epidemic model with MCMC
bioint ingest --sources who,cdc,ecdcStream surveillance feeds
bioint forecast --horizon 12w --ensemble 100Incidence forecast ensemble
bioint rt --window 7d --ci 0.95R_t with 95% credible interval
bioint pipeline --phase all --verboseFull pipeline ingest→model→deliver
bioint export --format json --streamExport to API/webhook

Domains

01

Disease Surveillance

Real-time epidemiological signals, outbreak patterns, pathogen genomics. Early-warning models for emerging threats and seasonal forecasting. Integrates WHO, CDC, ECDC, and regional surveillance networks. Compartmental models (SIR, SEIR) and agent-based simulations.

  • Epidemic curves
  • Genomic surveillance
  • Variant tracking
02

R&D Pipeline Intelligence

Drug development pipelines, clinical trial outcomes, regulatory milestones. Forecast approval probabilities and market entry timelines. Coverage of 12,000+ pipeline assets across therapeutic areas. Bayesian success-rate modeling.

  • Phase progression
  • Trial success rates
  • Patent landscapes
03

Healthcare Infrastructure

Hospital capacity, supply chain resilience, workforce dynamics. Model cascading impacts of demand shocks and resource constraints. Used by public health agencies and hospital networks. Queueing and network-flow optimization.

  • Bed occupancy
  • Supply chain risk
  • Workforce gaps
04

Bioeconomic Modeling

Connect biomedical events to economic outcomes. GDP impact of pandemics, biotech valuation drivers, healthcare spending trajectories. Cited in policy and investment research. CGE and DSGE integration.

  • Economic impact
  • Sector valuation
  • Spending forecasts

Drug Development Funnel

Attrition from discovery through approval — industry-standard funnel. Phase transition probabilities derived from Tufts CSDD and FDA approval databases.

DiscoveryPreclinicalPhase IPhase IIPhase IIISubmissionApproval025005000750010000

Pipeline

01

Ingest

Clinical, genomic, regulatory, and market data from 2,400+ validated sources.

02

Normalize

Unified schemas, entity resolution, temporal alignment.

03

Model

Statistical and ML models for forecasting and scenario analysis.

04

Deliver

Dashboards, APIs, and reports for researchers and decision-makers.

Coverage

2,400+Data sources
180Disease signals
12,000+Pipeline assets
DailyUpdate frequency

Data Integrations

ClinicalTrials.govWHO FluNetCDC DataEMAFDAGISAIDPubMedPatent databases

Data Types

Clinical Trials

Phase progression, enrollment, endpoints, regulatory submissions.

Genomic & Proteomic

Variant surveillance, expression data, biomarker discovery signals.

Regulatory

FDA, EMA, global agency filings, approvals, safety signals.

Epidemiological

Surveillance data, outbreak reports, incidence modeling inputs.

Market & Economic

Pricing, reimbursement, healthcare spending, sector indices.

Use Cases

Pharmaceutical Strategy

R&D portfolio optimization, competitive intelligence, market entry timing.

Public Health

Epidemic preparedness, resource allocation, policy scenario modeling.

Investment Research

Biotech valuation, clinical trial catalysts, sector rotation signals.

Supply Chain

Drug shortage prediction, manufacturing risk, logistics optimization.